On very rare occasion, some people, when first receiving intravenous infusions, have experienced the so-called Herxheimer Effect, a result of infusions very efficiently neutralizing pathogens and occasionally stimulating immunities too fast for the body to dispose toxins through normal elimination channels. This forces the body to utilize the secondary eliminative organs: lungs, sinuses, skin, and more. Experiences that may feel like a slight cold or the flu, loose bowels, shivers, etc. The skin may eliminate stored toxins, perhaps producing minor, temporary skin eruptions – all part of elimination of toxins that cause premature aging and skin problems, and are considered beneficial reactions, in that the immune system has been activated, and is working to heal from pathogens and toxins.